Benfotiamine: The Magical Cure of Your Stress


In this post, we’ll be covering what Benfotiamine is and why it’s important for our brain. As a part of the anti-oxidant family, Benfotiamine is pharmaceutical-grade acetylcysteine that’s taken orally and works to protect neural tissues from age-related damage. With its high oxidative stress levels, the brain gets easy access to oxygen molecules that the body needs in order to prevent the manifestation of diseases such as Alzheimer’s disease or Parkinson’s disease.

Benfotiamine is very similar to other forms of acetylcysteine, and the only difference is its pharmaceutical grade. Benfotiamine is also much more expensive than other forms of acetylcysteine on the market. There are many Benfotiamine benefits and side effects as well. You will read about this in this article.


What is Benfotiamine?

As we age, our bodies become more prone to oxidative stress. Oxidative stress occurs when the body becomes overburdened with oxygen molecules, which can cause inflammation, oxidation in cells, and tissue damage – leading to any number of diseases such as heart disease and diabetes. With any level of oxidative stress, inflammatory response and tissue damage will occur. The best thing that we can do is to prevent the oxidation of tissue, to begin with by having the proper levels of antioxidants in our body at all times.

Currently, one of the most influential anti-oxidants in the world is Benfotiamine. This anti-oxidant works primarily through its benzoate group, which becomes free when it’s taken orally and then attaches itself to oxidized compounds within neural tissues. The benzoate group prevents oxidation from happening. The more oxidized compounds that we have, the more oxidized compounds our bodies will turn to. Our bodies are smart and will take advantage of the free molecules of oxygen that we’re giving them; this is what leads to all of our diseases.

One way that we can easily prevent oxidative stress from occurring is by drinking either a lot of water or taking a high concentration of Benfotiamine (that has been purified so that it’s free from other types of other metabolites). You can do this by taking the whole pill, which will have significantly fewer benefits than the compound’s ability to interact with oxygen molecules. There are many Benfotiamine diabetes benefits.

Benfotiamine and health

Benfotiamine is an enhancer in that it enhances the body’s ability to absorb and use other nutrients. Benfotiamine is a chemical compound that’s derived from thiamine or vitamin B1. It helps the body process folic acid and glucose, and it also prevents blood sugar levels from increasing too much. This natural substance can help to treat or prevent many different diseases, such as:

  • Healthy Aging
  • Diabetes
  • Cardiovascular disease
  • Hyperlipidemia
  • Hypertension
  • Depression
  • Parkinson’s Disease
  • Autism
  • Alzheimer’s disease

1. Healthy Aging:

Healthy aging is the lifelong process of developing and maintaining a higher level of physical, mental, and social well-being as you grow older. Healthy aging not only impacts the individual but has an impact on society and culture too. The ability to age successfully is an increasingly important topic as people are living longer than ever before.

2. Diabetes:

Diabetes is a chronic and progressive disease. It can affect the entire body, from the brain to the feet. Common symptoms of diabetes include increased thirst, increased urination, sudden weight loss, and fatigue. Other common symptoms are blurred vision and erectile dysfunction in men. Diabetes is diagnosed with a fasting glucose test or an oral glucose tolerance test (OGTT). A person who maintains tight control over his or her blood sugar levels typically won’t experience any unusual symptoms other than possible tingling of hands and feet due to nerve damage caused by high blood sugars.

3. Cardiovascular disease:

Cardiovascular disease is a major threat to the health of society. It causes about 17.3 million deaths worldwide each year, and its incidence is projected to increase in the future because of increases in population size, aging, and economic development.

Cardiovascular disease is a general term for several different diseases that affect your heart or blood vessels. These diseases include:

  • Coronary artery disease (CAD)
  • High blood pressure (hypertension)
  • Stroke
  • Congestive heart failure
  • Angina
  • Heart attack (myocardial infarction, MI)

4. Hyperlipidemia:

Hyperlipidemia is a condition that can occur when a person has too many lipids in their blood. It can lead to cardiovascular disease and an increased risk of developing cardiovascular diseases, stroke, or several different types of cancer. The primary cause of hyperlipidemia is high levels of total cholesterol and triglycerides in the bloodstream. There are three primary types of hyperlipidemia:

  • Hypercholesterolemia (also known as high LDL)
  • High triglycerides
  • Low HDL

5. Hypertension:

Hypertension is the medical term for high blood pressure. The National Institutes of Health define it as a condition in which “the force or pressure of the blood against the artery walls is too high, even when the heart beats and pumps normally and there are no signs of heart disease.”

High blood pressure, also called hypertension, can lead to serious health issues such as stroke, heart attack, and kidney failure. If you have increased urination at night or your ankles swell, you should talk with your doctor about whether you have high blood pressure.

6. Depression:

Depression is a mental disorder that has a significant impact on the lifespan and quality of life. It’s been documented that individuals have an increased risk of developing depression later in life, and there’s been evidence of neurobiological abnormalities in persons with both depressive and anxiety disorders.

Depression is classified as an inflexible syndrome, which means that it has features found across many diagnostic categories (such as mood disorders, personality disorders, or eating disorders) while suffering from unique symptoms.

7. Parkinson’s Disease:

Parkinson’s disease is a movement disorder that affects the way the body controls its muscles and movements. Symptoms of Parkinson’s disease vary among people and may include difficulty moving, shaking, rigidity, stooped posture, balance problems, or freezing movements.

8. Autism:

Autism is a developmental disorder that affects an individual’s ability to communicate, socialize, and behave. It can be divided into three different categories: autistic disorder, Asperger’s syndrome, and PDD-NOS (pervasive developmental disorder not otherwise specified). The causes of autism are also unknown but it can be triggered by various factors including genetics and environmental toxins. Recognized early symptoms of autism include lack of social interaction and difficulty with communication skills.

9. Alzheimer’s disease:

Alzheimer’s is one of the most common forms of dementia. The disease causes a progressive decline in memory and thinking skills, and eventually loss of physical function. Alzheimer’s is caused by a buildup in the brain of plaques made up principally of beta-amyloid protein, neurofibrillary tangles formed principally from tau protein, and cell loss in parts of the cerebral cortex (especially in layers II and IV) where there are large neurons with synapses that support cognitive functions like learning and memory.

Health benefits of Benfotiamine

Benfotiamine is a supplement that is very effective at improving blood glucose levels, reducing oxidative stress, and protecting cells from damage. Benfotiamine supplements are typically taken in doses of 100-300 mg per day. People, who are diabetic, have high blood glucose levels or impaired insulin function may see the most benefit from Benfotiamine supplementation. More studies need to be done for it to become a recommended medical treatment for diabetes.

All medication prescribed by your healthcare provider must be taken as directed.

Benfotiamine is effective at lowering blood glucose levels after meals and improving insulin sensitivity in patients with type-2 diabetes.

Benefits of Benfotiamine

Diabetic neuropathy

The symptoms of nerve damage associated with diabetes include numbness, burning, tingling, and prickling sensations (often described as “pins and needles”). The b1 Benfotiamine benefits may help treat diabetic neuropathy because it improves glucose tolerance and lowers levels of AGEs, which may have a role in the progression of nerve injury.

Alzheimer’s disease

The Benfotiamine benefits dr axe reduced discomfort and improved cognitive function in mice. Although Benfotiamine did not directly reduce levels of amyloid-beta in mouse brains, it may have indirectly interacted with insulin and other signaling molecules that play a role in AGE formation and clearance, the researchers said. Benfotiamine has been shown to be an agonist for metallothionein, an antioxidant enzyme found in rats. The effect of metallothionein on neuronal cells is unknown but may result in less oxidative stress that can lead to neurodegenerative diseases such as Alzheimer’s disease.

Amyotrophic lateral sclerosis (ALS)

Dietary adjustments that lower oxidative stress or the build-up of damaging metabolic processes in the body may delay the course of ALS. The mega Benfotiamine benefits may have a therapeutic role in ALS because it increases the activity of metallothionein and decreases oxidative stress in some animals. Benfotiamine improved symptoms and disease progression in persons with ALS, according to a Phase II clinical study.


Benfotiamine was shown to reduce the accumulation of AGEs, which are thought to be related to cataract formation. Cataracts also result from inflammation, which can be reduced by Benfotiamine. The Benfotiamine benefits dr axe may also prevent new damage in otherwise healthy individuals.

Cardiovascular disease

AGEs are bound to proteins and may cause heart damage by activating inflammatory cells in the blood vessel walls. Benfotiamine’s radical scavenging activity can prevent damage in animal models of atherosclerosis or hardening of the arteries.

The equivalent of 300 mg per day of Benfotiamine has been shown to improve cardiovascular health in people with diabetes. More research is needed to see if this is also beneficial for people who do not have diabetes.

Parkinson’s disease

In laboratory tests, Benfotiamine increased levels of glutathione and reduced levels of oxidative stress markers in human cells that were exposed to a neurotoxin or chemical inducing Parkinson’s-like symptoms.

Overcoming alcohol dependence

Chronic alcohol intake lowers glutathione levels and causes gastrointestinal damage. The mega Benfotiamine benefits may act as a protective agent by reducing intestinal inflammation and oxidative stress caused by alcohol.


Benfotiamine’s potential as a calorie restriction mimetic in humans has been studied. No human clinical studies have shown calorie restriction can increase life span and prevent disease, but some research has suggested that Benfotiamine can have similar effects, such as increasing longevity in mice. All of Benfotiamine’s benefits come from its ability to increase antioxidant activity and its ability to protect the membranes of mitochondria in cells.

In tissue cultures, Benfotiamine increased the expression of genes that are essential for the production of energy. More research is needed to determine the mechanisms by which Benfotiamine affects cellular metabolism.

Benfotiamine for smoking

Smoking leads to endothelial dysfunction in the lungs, which can be reversed by antioxidants. Benfotiamine is a fat-soluble form of thiamine (vitamin B1) that is easily taken up by cell membranes and can prevent oxidative stress induced by cigarette smoke. Benfotiamine has been studied for its ability to reduce the frequency and severity of seizures associated with epilepsy and for other brain disorders. Toxicity from high doses of Benfotiamine appears to be low, even in people who are genetically predisposed to high levels of oxidative stress.


Various studies shows that Benfotiamine may have antitumor potential as benfomax benefits include that it inhibits angiogenesis and tumor cell growth in an orthotopic model of human colorectal cancer.


At pH 6, Benfotiamine is a powerful antioxidant that prevents lipid peroxidation caused by peroxynitrite. It has also been reported to have antioxidant effects in a variety of animal models, with vitamin B-responsive elements being identified as one of the main targets. Benfotiamine has also successfully been used to render special cadmium-tolerant salt-resistant plants more resistant against metal phytotoxicity. Benfotiamine is the thiamine derived from vitamin B1, the most commonly encountered form of thiamin and an essential nutrient, which is required for the normal function of all body cells and tissues.

Side Effects of Benfotiamine

Benfotiamine is safe to use and it doesn’t have too many side effects. The side effects of Benfotiamine capsules are given below:

  • Nausea
  • Skin rash
  • Diarrhea
  • Hair loss
  • Weight gain
  • Stomach discomfort
  • Decrease in blood pressure
  • Body odor